Dab tsi yog qhov txawv ntawm selenomethionine thiab l-selomethionine?
2024-10-17 15:28:46
Selenium yog ib qho tseem ceeb ntawm cov pob zeb hauv av uas ua lub luag haujlwm tseem ceeb hauv ntau lub cev ua haujlwm, suav nrog kev tiv thaiv antioxidant, thyroid hormone metabolism, thiab kev tiv thaiv kab mob. Ob hom selenium ntxiv yog selenomethionine thiab L-selenomethionine. Txawm hais tias cov tebchaw no yuav zoo sib xws, muaj qee qhov sib txawv tseem ceeb ntawm lawv uas tsim nyog tshawb nrhiav. Hauv tsab xov xwm no, peb yuav piav qhia txog qhov sib txawv ntawm selenomethionine thiab L-selenomethionine, tshuaj xyuas lawv cov bioavailability, kev ua haujlwm antioxidant, thiab cov metabolism hauv lub cev.
Puas muaj qhov sib txawv hauv Bioavailability ntawm Selenomethionine thiab L-Selenomethionine?
Bioavailability yog hais txog qhov twg thiab tus nqi ntawm cov khoom yog absorbed thiab yuav muaj nyob rau hauv lub cev. Thaum nws los txog rau selenomethionine thiab L-selenomethionine, muaj qhov sib txawv ntawm lawv cov bioavailability.
Selenomethionine yog ib qho selenium-muaj cov amino acid uas muaj nyob rau hauv ob hom: D-selenomethionine thiab L-selenomethionine. L-selenomethionine yog daim ntawv tshwm sim nyob rau hauv cov zaub mov thiab suav hais tias yog qhov ntau bioavailable ntawm ob. Qhov no yog vim tib neeg lub cev tau tsim los paub txog thiab siv L-amino acids zoo dua li lawv cov D-tus neeg sawv cev.
L-selenomethionine tau pom tias muaj kev nqus zoo dua thiab khaws cia hauv lub cev piv rau lwm hom selenium, suav nrog selenite thiab selenate. Qhov kev txhim kho bioavailability no yog vim nws lub peev xwm los ncaj qha mus rau hauv cov protein nyob rau hauv qhov chaw ntawm cov amino acid methionine. Raws li qhov tshwm sim, L-selenomethionine tuaj yeem khaws cia hauv cov ntaub so ntswg thiab muab kev tso tawm ntau dua ntawm selenium dhau sijhawm.
Ntawm qhov tod tes, selenomethionine tsis muaj "L" prefix feem ntau yog hais txog kev sib xyaw ntawm D- thiab L-forms. Txawm hais tias qhov sib xyaw ntawm haiv neeg no tseem muaj cov L-daim ntawv bioavailable, nws kuj suav nrog qhov tsis zoo siv D-daim ntawv. Yog li ntawd, tag nrho bioavailability ntawm selenomethionine yuav qis dua me ntsis ntawm cov ntshiab L-selenomethionine.
Nws tsim nyog sau cia tias lub cev tuaj yeem hloov selenomethionine mus rau lwm yam kev ua haujlwm lom neeg ntawm selenium, xws li selenocysteine, uas tau muab tso rau hauv selenoproteins. Cov txheej txheem hloov dua siab tshiab no txhawb nqa tag nrho bioavailability thiab kev ua tau zoo ntawm ob qho tib si selenomethionine thiab L-selenomethionine ua selenium qhov chaw.
Selenomethionine thiab L-Selenomethionine cuam tshuam li cas rau Antioxidant Activity?
Selenium muaj npe nrov rau nws cov khoom muaj zog antioxidant, thiab ob qho tib si selenomethionine thiab L-selenomethionine pab txhawb kom lub cev tiv thaiv antioxidant. Txawm li cas los xij, muaj qee qhov nuances nyob rau hauv yuav ua li cas cov tebchaw no cuam tshuam rau kev ua haujlwm antioxidant.
L-selenomethionine, yog cov khoom ntuj tsim muaj nyob hauv cov khoom noj, tau yooj yim nkag mus rau hauv selenoproteins, uas yog thawj tus neeg nruab nrab ntawm selenium's antioxidant teebmeem. Cov selenoproteins no suav nrog glutathione peroxidases, thioredoxin reductases, thiab selenoprotein P, tag nrho cov no ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv cov hlwb los ntawm oxidative kev nyuaj siab thiab dawb radical puas.
Kev sib xyaw ua ke zoo ntawm L-selenomethionine rau hauv selenoproteins txhais tau hais tias nws tuaj yeem muaj peev xwm muab cov nyhuv antioxidant tam sim ntawd thiab txhawb nqa. Qhov no yog qhov tseem ceeb tshwj xeeb hauv cov ntaub so ntswg uas muaj cov metabolism hauv siab, xws li lub hlwb, cov thyroid, thiab cov qog nqaij hlav, qhov twg oxidative kev nyuaj siab tuaj yeem cuam tshuam txog kev noj qab haus huv.
Selenomethionine, raws li kev sib xyaw ntawm D- thiab L-cov ntaub ntawv, tseem muaj txiaj ntsig rau kev ua haujlwm antioxidant, tab sis nws cov teebmeem yuav ua tau me ntsis hais los yog tam sim ntawd piv rau cov ntshiab L-selenomethionine. Daim ntawv D-daim ntawv yuav xav tau cov kauj ruam ntxiv hauv metabolic ua ntej nws tuaj yeem siv tag nrho hauv txoj hauv kev antioxidant, uas yuav ua rau qeeb lossis txo cov lus teb antioxidant.
Ob daim ntawv ntawm selenomethionine tau pom tias txhim khu kev ua haujlwm ntawm cov enzymes antioxidant, xws li superoxide dismutase thiab catalase. Qhov no synergistic nyhuv nrog rau lwm cov kab mob antioxidant ntxiv amplifates lawv lub peev xwm tiv thaiv oxidative puas tsuaj.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov tshuaj tua kab mob antioxidant ntawm selenomethionine thiab L-selenomethionine yog nyob ntawm koob tshuaj. Thaum noj selenium txaus yog qhov tseem ceeb rau kev pom kev ua haujlwm antioxidant, ntau ntxiv tuaj yeem ua rau muaj kev cuam tshuam oxidant thiab muaj peev xwm toxicity. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tau ua raws li kev pom zoo ntau npaum li cas thiab sab laj nrog tus kws kho mob ua ntej pib ua cov selenium supplementation regimen.
Selenomethionine thiab L-Selenomethionine Metabolized hauv lub cev li cas?
Cov metabolism hauv selenomethionine thiab L-selenomethionine nyob rau hauv lub cev muaj ntau yam txheej txheem uas thaum kawg txiav txim siab lawv lom thiab cov teebmeem. Kev nkag siab txog cov txheej txheem metabolic no tuaj yeem muab kev nkag siab txog qhov sib txawv ntawm ob hom selenium.
L-selenomethionine, yog lub ntuj tsim, ua raws li txoj hauv kev zoo hauv lub cev. Thaum noj, nws tuaj yeem muab tso ncaj qha rau hauv cov protein nyob rau hauv qhov chaw ntawm methionine, vim tias lub cev cov protein synthesis machinery tsis txawv ntawm ob. Cov cuab yeej tshwj xeeb no tso cai rau L-selenomethionine khaws cia hauv cov ntaub so ntswg, tsim kom muaj selenium cia uas tuaj yeem maj mam tso tawm dhau sijhawm.
Cov metabolism ntawm L-selenomethionine kuj koom nrog nws txoj kev hloov mus rau selenocysteine, 21st amino acid siv hauv kev sib txuas ntawm selenoprotein. Cov txheej txheem no tshwm sim los ntawm txoj kev trans-sulfuration, qhov twg L-selenomethionine yog thawj zaug hloov mus rau selenocystathionine, tom qab ntawd mus rau selenohomocysteine, thiab thaum kawg mus rau selenocysteine. Cov selenocysteine no tuaj yeem muab tso rau hauv ntau yam selenoproteins, suav nrog glutathione peroxidases thiab thioredoxin reductases.
Selenomethionine, raws li kev sib xyaw ntawm D- thiab L-forms, ua rau muaj qhov sib txawv me ntsis ntawm txoj hmoo metabolic. Thaum daim ntawv L-daim ntawv ua raws tib txoj hauv kev raws li tau piav qhia saum toj no, daim ntawv D-daim ntawv xav tau cov kauj ruam ntxiv rau kev siv. Lub cev yuav tsum xub hloov D-selenomethionine rau nws L-daim ntawv los ntawm cov txheej txheem hu ua racemization, uas yog catalyzed los ntawm cov enzymes tshwj xeeb. Cov kauj ruam ntxiv no tuaj yeem ua rau qeeb tag nrho cov metabolism thiab kev siv selenium los ntawm selenomethionine piv rau cov ntshiab L-selomethionine.
Ob daim ntawv tseem tuaj yeem ua rau methylation ncaj qha los tsim methylselenol, ib qho tseem ceeb metabolite hauv selenium's anticancer thiab chemopreventive cov dej num. Cov txheej txheem no yog txhawb nqa los ntawm enzyme γ-lyase, uas cleaves selenomethionine los tsim methylselenol.
Lwm qhov tseem ceeb ntawm selenomethionine thiab L-selomethionine metabolism yog lawv cov kev cuam tshuam nrog methionine pas dej hauv lub cev. Txij li cov tebchaw no tuaj yeem hloov pauv rau methionine hauv cov protein synthesis, lawv tuaj yeem cuam tshuam rau methionine metabolism thiab lwm txoj hauv kev, xws li lub voj voog methylation. Qhov kev sib cuam tshuam no qhia txog qhov tseem ceeb ntawm kev tswj hwm qhov sib npaug ntawm selenium thiab methionine kom tau txais kev noj qab haus huv zoo.
Lub excretion ntawm selenium ntau dhau los ntawm selenomethionine thiab L-selenomethionine feem ntau tshwm sim los ntawm cov zis, nrog me me tshem tawm los ntawm quav thiab exhaled cua. Lub cev muaj cov txheej txheem zoo los tswj cov qib selenium, hloov cov selenium ntau dhau mus rau cov ntaub ntawv tsis muaj tshuaj lom xws li selenosugars thiab methylated metabolites rau excretion.
xaus
Hauv kev xaus, thaum selenomethionine thiab L-selenomethionine qhia ntau qhov sib xws hauv lawv cov metabolism, cov ntshiab L-daim ntawv yuav muaj qhov zoo me ntsis ntawm kev siv ncaj qha thiab kev koom ua ke rau hauv selenoproteins. Txawm li cas los xij, ob qho tib si yog cov txiaj ntsig zoo ntawm selenium thiab pab txhawb rau lub cev selenium pas dej ua ke thiab cov txiaj ntsig kev noj qab haus huv. Yog tias koj xav paub ntau ntxiv txog cov khoom no, koj tuaj yeem tiv tauj peb ntawm sales@pioneerbiotech.com.
References
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