Lactoferrin yog dab tsi?

Lactoferrin yog ib tug multifunctional glycoprotein pom nyob rau hauv ntau yam biological kua, xws li mis nyuj, qaub ncaug, kua muag, thiab mucus secretions. Nws plays lub luag haujlwm tseem ceeb hauv lub cev tiv thaiv kab mob hauv lub cev thiab muaj ntau yam kev ua haujlwm lom neeg. Nov yog cov ntsiab lus ntawm lactoferrin thiab nws lub luag haujlwm:

Lactoferrin ua dab tsi?

Lactoferrin, muaj ntau yam protein ntau pom nyob rau hauv cov kua dej sib txawv xws li ntws, nto qaub ncaug, kua muag, thiab lub cev dej, ua haujlwm rau ob peb yam tseem ceeb hauv lub cev:

Antimicrobial Movement: Nws qhia tau hais tias muaj zog tiv thaiv kab mob, tiv thaiv kev loj hlob ntawm microbes, kab mob, kab mob, thiab lwm yam kab mob. Nws ua tiav qhov no los ntawm kev txiav cov xovxwm, ib qho tseem ceeb ntxiv rau kev txhim kho microbial, tom qab tsis kam lees cov kab mob ntawm cov xovxwm thiab txwv lawv lub peev xwm los tsim dua tshiab.

Txoj Kev Nyab Xeeb: Nws ua rau muaj qhov sib txawv sib npaug ntawm cov tshuaj tiv thaiv, txhim kho kev txav ntawm cov hlwb zoo xws li macrophages, neutrophils, thiab T hlwb. Nws pab nyob rau hauv kev lees paub thiab kev rhuav tshem cov kab mob thaum tswj cov tshuaj tiv thaiv hluav taws, ua kom muaj kev nyab xeeb zoo rau cov kab mob.

Xovxwm Thauj thiab Metabolism: Raws li cov hlau khi cov protein, Nws suav nrog hauv kev thauj thiab xa xovxwm hauv lub cev. Nws khi rau cov xovxwm nrog qhov siab siab, xa cov xovxwm mus rau cov hlwb uas xav tau nws rau cov ntaub ntawv metabolic, xws li cov qe ntshav liab thiab ua pa ntawm tes. Tsis tas li ntawd, nws ua rau muaj kev sib txawv tswj cov xovxwm homeostasis los ntawm sequestering abundance xovxwm thiab cia siab tias nws tsub zuj zuj.

Txoj Kev Noj Qab Haus Huv Zoo: Nws pab txhawb txoj hnyuv kom muaj kev noj qab haus huv los ntawm kev sib npaug ntawm cov hnyuv microbiota thiab txhawb kev astuteness ntawm txoj hnyuv. Nws txhawb txoj kev loj hlob ntawm cov kab mob microscopic uas muaj txiaj ntsig zoo thaum tiv thaiv kev sib kis ntawm cov kab mob phem, ua rau muaj kev sib txawv kom tsis txhob muaj kab mob hauv plab thiab o.

Anti-inflammatory Impacts: Lactoferrin muaj anti-inflammatory zog, txo aggravation thiab cov ntaub so ntswg puas. Nws cuam tshuam lub cim ntawm pro-inflammatory cytokines thiab txhawb kev txav ntawm cov tshuaj tiv thaiv kab mob, txhawb kev txiav txim siab ntawm kev khaus thiab kho cov ntaub so ntswg.

Antioxidant Movement: Nws qhia tau hais tias antioxidant zog, rummaging dawb radicals thiab ua kom cov hlwb los ntawm oxidative kev puas tsuaj. Nws ua rau muaj qhov sib txawv nruab nrab ntawm cov teb cov pa oxygen (ROS) thiab cov kab mob nitrogen teb (RNS), uas tuaj yeem ua rau muaj kev puas tsuaj ntawm tes thiab ua rau muaj mob sib txawv thiab cov txheej txheem kev laus.

Kev Kho Hniav: Nws yog koom nrog hauv kev npaj lub qhov txhab rov qab, txhim kho cov ntaub so ntswg thiab rov qab los. Nws txhawb kev sib npaug ntawm tes, tweaks cov tshuaj tiv thaiv fiery, thiab txhim kho qhov kev txiav txim ntawm kev loj hlob hloov pauv muaj nyob rau hauv qhov txhab rov qab, xws li hloov kev loj hlob yam-beta (TGF-β) thiab vascular endothelial kev loj hlob xam (VEGF).

Lub luag haujlwm ntawm Lactoferrin yog dab tsi?

Lub muaj nuj nqi ntawm lactoferrin encompasses ntau lub luag haujlwm tseem ceeb hauv lub cev:

1. Antimicrobial Activity: Nws ua raws li cov tshuaj tua kab mob ntuj, inhibiting kev loj hlob ntawm cov kab mob, kab mob, fungi, thiab lwm yam kab mob. Nws ua tiav qhov no los ntawm kev khi rau hlau, ib qho tseem ceeb rau kev loj hlob ntawm microbial, thiab ua rau nws tsis muaj rau cov kab mob, yog li txwv lawv lub peev xwm los tsim thiab ua rau muaj kab mob.

2. Immune Regulation: Nws plays lub luag haujlwm tseem ceeb hauv kev tswj lub cev tiv thaiv kab mob. Nws pab hloov cov kev ua ntawm ntau lub cev tiv thaiv kab mob, xws li macrophages, neutrophils, thiab T hlwb, txhim kho lawv lub peev xwm paub txog thiab rhuav tshem cov kab mob. Nws kuj pab tswj cov kab mob inflammatory, txhawb kev sib npaug ntawm lub cev tiv thaiv kab mob thiab tiv thaiv kev mob ntau dhau.

3. Hlau Thauj thiab Metabolism: Nws yog cov hlau khi cov protein uas thauj thiab tswj cov hlau hauv lub cev. Nws khi rau hlau nrog siab affinity, pab thauj nws hla cell membranes thiab xa mus rau cov hlwb uas yuav tsum tau nws rau cov txheej txheem metabolic tseem ceeb, xws li cov qe ntshav liab tsim thiab ua pa ntawm tes. Nws kuj sequesters tshaj hlau, tiv thaiv nws tsub zuj zuj thiab muaj peev xwm toxicity.

4. Gut Health: Nws plays lub luag haujlwm hauv kev tswj lub plab noj qab haus huv thiab kev ncaj ncees. Nws pab kho qhov muaj pes tsawg leeg ntawm plab microbiota, txhawb kev loj hlob ntawm cov kab mob uas muaj txiaj ntsig zoo thaum inhibiting kev loj hlob ntawm cov kab mob phem. Nws kuj txhawb kev ncaj ncees ntawm txoj hnyuv, pab tiv thaiv kab mob plab hnyuv, o, thiab permeability.

5. Anti-inflammatory Effects: Nws muaj cov tshuaj tiv thaiv kab mob, pab txo qhov mob thiab cov ntaub so ntswg puas. Nws inhibits zus tau tej cov pro-inflammatory cytokines thiab txhawb cov kev ua ntawm anti-inflammatory mediators, pab rau kev daws teeb meem ntawm o thiab cov ntaub so ntswg kho txheej txheem.

Lactoferrin ua dab tsi?

Lactoferrin ua haujlwm ntau yam hauv lub cev:

• Boosts lub cev tiv thaiv kab mob: Nws txhim kho lub cev tiv thaiv kab mob ua haujlwm thiab txhawb kev tsim cov tshuaj tiv thaiv kab mob, pab lub cev tiv thaiv kab mob.

• Txhawb lub plab noj qab haus huv: Nws nthuav tawm cov khoom prebiotic los ntawm kev noj cov kab mob plab uas muaj txiaj ntsig, txhawb kev noj qab haus huv hauv plab hnyuv ib puag ncig, thiab txo qis kev pheej hmoo ntawm kev mob plab.

• Txhawb kev nqus hlau: Nws pab txhawb kev nqus ntawm cov hlau noj zaub mov, tiv thaiv cov hlau deficiency anemia.

• Txhim kho qhov txhab zoo: Nws txhawb kev kho cov ntaub so ntswg thiab rov tsim dua tshiab, ua kom cov txheej txheem kho qhov txhab thiab qhov txhab.

• Muab cov teebmeem antioxidant: Nws tshem tawm cov teeb meem dawb radicals, tiv thaiv cov hlwb thiab cov ntaub so ntswg los ntawm oxidative kev nyuaj siab thiab kev puas tsuaj.

Ntawm Pioneer Biotech, peb tshwj xeeb hauv cov khoom zoo lactoferrin cov khoom. Yog tias koj xav kawm ntxiv lossis yuav cov tshuaj lactoferrin, thov koj xav tiv tauj peb ntawm sales@pioneerbiotech.com.

References:

1. Zimecki, M., & Artym, J. (2020). Lactoferrin hauv kev noj qab haus huv thiab kab mob. Postepy Higieny I Medycyny Doswiadczalnej, 74, 984–1004.

2. Manzoni, P., Meyer, M., Stolfi, I., Rinaldi, M., Cattani, S., Pugni, L., … Mostert, M. (2020). plab hnyuv Lactoferrin rau Kev Kho Mob Sepsis thiab Necrotizing Enterocolitis hauv Neonates: Kev Tshawb Fawb Txog Kev Tshawb Fawb. Pharmaceuticals (Basel, Switzerland), 13(10), 337.

3. Wakabayashi, H., Oda, H., Yamauchi, K., Abe, F., & Motohashi, Y. (2017). Lactoferrin rau kev tiv thaiv kab mob sib kis. Phau ntawv Journal of infection and chemotherapy: official journal of the Japan Society of Chemotherapy, 23(3), 197–202.